Assay Report Card

Basic Information

ID: ALA4430356

Type: Binding

Description: Selectivity index, ratio of agonist activity at human RARalpha expressed in HEK293 cells assessed as increase in RARE-mediated transcription relative to bexarotene to agonist activity at human RXRalpha expressed in human HCT116 cells assessed as increase in RXRE-mediated transcription relative to bexarotene

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
300.445.605.60
352.485.295.29
367.494.994.99
353.474.684.68
383.516.346.34
367.494.994.99
365.526.206.20
369.486.036.03