Basic Information
ID: ALA4430357
Type: ADME
Description: Agonist activity at human RXRalpha/LXRalpha expressed in human HCT116 cells assessed as reduction in SREBP-mediated transcription activity at 100 nM incubated for 24 hrs by luciferase reporter gene assay relative to bexarotene
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4430357
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 352.48 | 5.29 | 5.29 |
| 367.49 | 4.99 | 4.99 |
| 386.51 | 4.82 | 4.82 |
| 366.51 | 5.60 | 5.60 |
| 353.47 | 4.68 | 4.68 |
| 351.49 | 5.89 | 5.89 |
| 384.54 | 5.65 | 5.65 |
| 383.51 | 6.34 | 6.34 |
| 367.49 | 4.99 | 4.99 |
| 365.52 | 6.20 | 6.20 |
| 369.48 | 6.03 | 6.03 |
| 353.47 | 4.68 | 4.68 |