Basic Information
ID: ALA4430358
Type: ADME
Description: Agonist activity at human RXRalpha/LXRalpha expressed in human HCT116 cells assessed as reduction in SREBP-mediated transcription activity at 100 nM incubated for 24 hrs by luciferase reporter gene assay in presence of 100 nM LXR agonist TO901317 relative to bexarotene
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4430358
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 352.48 | 5.29 | 5.29 |
| 367.49 | 4.99 | 4.99 |
| 366.51 | 5.60 | 5.60 |
| 353.47 | 4.68 | 4.68 |
| 351.49 | 5.89 | 5.89 |
| 367.49 | 4.99 | 4.99 |
| 369.48 | 6.03 | 6.03 |
| 353.47 | 4.68 | 4.68 |