Basic Information
ID: ALA4430527
Type: Binding
Description: Inhibition of human NOD1 over-expressed in HEK-Blue cells assessed as inhibition of C12-iE-DAP induced NF-kappaB transcriptional activity measured as residual activity at 25 uM preincubated for 1 hr followed by addition of C12-iE-DAP measured after 18 hrs by SEAP reporter gene assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Target: Nucleotide-binding oligomerization domain-containing protein 1(ALA1293222)
Document: ALA4428099
Inhibition of human NOD1 over-expressed in HEK-Blue cells assessed as inhibition of C12-iE-DAP induced NF-kappaB transcriptional activity measured as residual activity at 25 uM preincubated for 1 hr followed by addition of C12-iE-DAP measured after 18 hrs by SEAP reporter gene assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4430527
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 363.82 | 3.71 | 3.71 |
| 287.34 | 2.16 | 2.16 |
| 326.75 | 4.25 | 4.25 |
| 314.37 | 2.29 | 2.29 |
| 329.38 | 1.79 | 1.79 |
| 359.40 | 3.06 | 3.06 |
| 358.24 | 4.63 | 4.63 |
| 397.37 | 4.07 | 4.07 |
| 293.20 | 3.88 | 3.88 |
| 319.40 | 4.74 | 4.74 |
| 300.83 | 4.35 | 4.35 |
| 374.37 | 2.96 | 2.96 |
| 321.42 | 4.99 | 4.99 |
| 297.33 | 4.01 | 4.01 |
| 343.40 | 3.36 | 3.36 |
| 293.37 | 4.17 | 4.17 |
| 258.75 | 3.23 | 3.23 |
| 272.78 | 3.53 | 3.53 |
| 347.34 | 4.89 | 4.89 |
| 298.82 | 4.10 | 4.10 |
| 337.65 | 3.99 | 3.99 |
| 313.78 | 4.52 | 4.52 |
| 347.37 | 3.19 | 3.19 |
| 279.34 | 3.87 | 3.87 |