Basic Information
ID: ALA4430528
Type: Binding
Description: Inhibition of human NOD2 over-expressed in HEK-Blue cells assessed as inhibition of C12-iE-DAP induced NF-kappaB transcriptional activity preincubated for 1 hr followed by addition of C12-iE-DAP measured after 18 hrs by SEAP reporter gene assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4430528
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 363.82 | 3.71 | 3.71 |
| 257.72 | 3.32 | 3.32 |
| 287.34 | 2.16 | 2.16 |
| 293.20 | 3.88 | 3.88 |
| 374.37 | 2.96 | 2.96 |
| 343.40 | 3.36 | 3.36 |
| 293.37 | 4.17 | 4.17 |
| 307.35 | 3.81 | 3.81 |
| 347.37 | 3.19 | 3.19 |