Basic Information
ID: ALA4430892
Type: Functional
Description: Inhibition of DEM-induced collapse of mitochondrial membrane potential in FRDA patient derived lymphocyte GM15850 assessed as intact mitochondrial membrane potential at 100 nM pre-incubated for 16 hrs followed by DEM addition for 120 mins by TMRM dye based flow cytometry (Rvb = 91.3 %)
Organism: Homo sapiens
Cell type: GM15850
Activity Charts
Bioactivity
Activity Types for Assay ALA4430892
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 393.62 | 6.28 | 6.28 |
| 445.69 | 7.35 | 7.35 |
| 391.60 | 6.17 | 6.17 |
| 405.63 | 6.42 | 6.42 |
| 459.72 | 7.74 | 7.74 |
| 419.65 | 6.81 | 6.81 |
| 473.75 | 8.13 | 8.13 |
| 389.63 | 6.72 | 6.72 |
| 433.68 | 7.20 | 7.20 |