Basic Information
ID: ALA4430907
Type: Binding
Description: Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 5 mins by liquid scintillation counting method
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4430907
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.39 | 3.55 | 3.55 |
| 450.31 | 4.62 | 4.62 |
| 435.84 | 3.90 | 3.90 |
| 366.40 | 1.72 | 1.72 |
| 435.84 | 3.90 | 3.90 |
| 335.34 | 1.98 | 1.98 |
| 451.91 | 4.37 | 4.37 |
| 426.28 | 4.85 | 4.85 |
| 496.93 | 5.28 | 5.28 |
| 431.42 | 3.25 | 3.25 |
| 351.34 | 1.69 | 1.69 |
| 363.39 | 2.30 | 2.30 |
| 451.46 | 4.40 | 4.40 |
| 351.34 | 1.69 | 1.69 |
| 335.34 | 1.98 | 1.98 |
| 436.83 | 4.11 | 4.11 |
| 351.34 | 1.69 | 1.69 |
| 435.84 | 3.90 | 3.90 |
| 295.32 | 2.19 | 2.19 |
| 349.36 | 1.91 | 1.91 |
| 419.39 | 3.38 | 3.38 |
| 365.36 | 1.62 | 1.62 |
| 445.88 | 4.30 | 4.30 |
| 361.38 | 2.38 | 2.38 |
| 359.37 | 1.47 | 1.47 |
| 415.42 | 3.55 | 3.55 |
| 389.45 | 4.03 | 4.03 |
| 420.81 | 2.63 | 2.63 |
| 436.83 | 4.11 | 4.11 |
| 436.83 | 4.11 | 4.11 |
| 421.81 | 3.51 | 3.51 |
| 364.42 | 2.87 | 2.87 |
| 507.52 | 4.82 | 4.82 |
| 363.78 | 3.96 | 3.96 |
| 435.84 | 3.90 | 3.90 |
| 445.88 | 4.30 | 4.30 |
| 379.39 | 2.01 | 2.01 |