Basic Information
ID: ALA4430912
Type: Binding
Description: Inhibition of fluorescent dsRNA probe binding to N-terminal His-tagged recombinant Ebola virus VP35 interferon inhibitory domain assessed as normalized intensity for DNA binding at 200 uM pre-incubated for 5 mins before dsRNA addition and measured after 5 mins by ethidium bromide displacement based EMSA method relative to control
Organism: Ebolavirus
Activity Charts
Bioactivity
Activity Types for Assay ALA4430912
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 492.56 | 6.78 | 6.78 |
| 380.99 | 3.82 | 3.82 |
| 111.14 | 1.00 | 1.00 |
| 454.48 | 2.67 | 2.67 |
| 436.38 | 2.63 | 2.63 |
| 435.54 | 0.69 | 0.69 |
| 465.54 | 4.76 | 4.76 |
| 462.38 | 1.77 | 1.77 |
| 336.31 | 0.21 | 0.21 |
| 316.40 | 2.72 | 2.72 |
| 206.25 | 1.71 | 1.71 |