Basic Information
ID: ALA4430985
Type: Binding
Description: Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells preincubated for 30 mins followed by addition of p-tyramine as substrate measured over 45 mins by Amplex Red MAO assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4430985
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 194.19 | -1.03 | -1.03 |
| 355.40 | 0.20 | 0.20 |
| 379.42 | 0.31 | 0.31 |
| 345.79 | 1.11 | 1.11 |
| 408.51 | 0.91 | 0.91 |
| 311.35 | 0.45 | 0.45 |
| 383.41 | 0.22 | 0.22 |
| 339.40 | 0.49 | 0.49 |
| 274.28 | -1.23 | -1.23 |
| 418.30 | 1.25 | 1.25 |
| 342.40 | 0.14 | 0.14 |
| 424.29 | 1.64 | 1.64 |
| 351.41 | 0.42 | 0.42 |
| 418.30 | 1.25 | 1.25 |
| 426.87 | 0.68 | 0.68 |
| 365.44 | 1.33 | 1.33 |
| 351.41 | 0.94 | 0.94 |
| 375.38 | 0.77 | 0.77 |
| 373.39 | 0.47 | 0.47 |
| 369.43 | 0.50 | 0.50 |
| 369.43 | 0.50 | 0.50 |
| 357.39 | 0.63 | 0.63 |
| 361.40 | 1.61 | 1.61 |
| 408.29 | 1.80 | 1.80 |
| 383.84 | 0.95 | 0.95 |
| 407.40 | 1.51 | 1.51 |
| 357.39 | 0.63 | 0.63 |
| 408.29 | 1.80 | 1.80 |
| 373.84 | 1.15 | 1.15 |
| 448.32 | 1.26 | 1.26 |
| 373.84 | 1.15 | 1.15 |
| 373.84 | 1.15 | 1.15 |
| 343.39 | -0.51 | -0.51 |
| 490.51 | 2.90 | 2.90 |
| 373.39 | 0.47 | 0.47 |
| 418.28 | 1.61 | 1.61 |
| 328.38 | -0.25 | -0.25 |
| 408.29 | 1.80 | 1.80 |
| 345.79 | 1.11 | 1.11 |
| 442.93 | 2.23 | 2.23 |
| 351.41 | 0.94 | 0.94 |
| 343.39 | -0.46 | -0.46 |
| 399.45 | 0.51 | 0.51 |
| 353.43 | 0.88 | 0.88 |
| 399.45 | 0.51 | 0.51 |
| 345.43 | 0.55 | 0.55 |
| 355.40 | -0.02 | -0.02 |
| 414.52 | 1.63 | 1.63 |
| 329.33 | 0.59 | 0.59 |
| 394.26 | 1.76 | 1.76 |
| 476.48 | 2.59 | 2.59 |
| 425.39 | 1.65 | 1.65 |
| 442.93 | 2.23 | 2.23 |
| 341.37 | 0.46 | 0.46 |
| 390.24 | 1.22 | 1.22 |
| 329.33 | 0.59 | 0.59 |
| 441.84 | 2.16 | 2.16 |
| 325.37 | 0.45 | 0.45 |
| 392.42 | 1.10 | 1.10 |
| 432.32 | 1.64 | 1.64 |
| 353.43 | 1.05 | 1.05 |
| 351.41 | 0.94 | 0.94 |
| 355.40 | 0.33 | 0.33 |
| 395.46 | 0.82 | 0.82 |
| 387.87 | 1.54 | 1.54 |