Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells at 10 uM preincubated for 30 mins followed by addition of p-t...

Basic Information

ID: ALA4430986

Type: Binding

Description: Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells at 10 uM preincubated for 30 mins followed by addition of p-tyramine as substrate measured over 45 mins by Amplex Red MAO assay relative to control

Format: BAO_0000219

Organism: Homo sapiens

Target: Monoamine oxidase B(ALA2039)

Document: ALA4428125

Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells at 10 uM preincubated for 30 mins followed by addition of p-tyramine as substrate measured over 45 mins by Amplex Red MAO assay relative to control: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4430986

Inhibition

Total(46)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
355.40	0.20	0.20
379.42	0.31	0.31
408.51	0.91	0.91
311.35	0.45	0.45
383.41	0.22	0.22
339.40	0.49	0.49
274.28	-1.23	-1.23
342.40	0.14	0.14
424.29	1.64	1.64
426.87	0.68	0.68
375.38	0.77	0.77
373.39	0.47	0.47
369.43	0.50	0.50
369.43	0.50	0.50
357.39	0.63	0.63
383.84	0.95	0.95
407.40	1.51	1.51
357.39	0.63	0.63
373.84	1.15	1.15
448.32	1.26	1.26
373.84	1.15	1.15
343.39	-0.51	-0.51
490.51	2.90	2.90
373.39	0.47	0.47
418.28	1.61	1.61
328.38	-0.25	-0.25
345.79	1.11	1.11
442.93	2.23	2.23
351.41	0.94	0.94
343.39	-0.46	-0.46
399.45	0.51	0.51
353.43	0.88	0.88
399.45	0.51	0.51
345.43	0.55	0.55
355.40	-0.02	-0.02
414.52	1.63	1.63
476.48	2.59	2.59
425.39	1.65	1.65
442.93	2.23	2.23
325.37	0.45	0.45
392.42	1.10	1.10
432.32	1.64	1.64
353.43	1.05	1.05
355.40	0.33	0.33
395.46	0.82	0.82
387.87	1.54	1.54