Basic Information
ID: ALA4431083
Type: Binding
Description: Antagonistic activity at alpha1B adrenoceptor in Sprague-Dawley rat spleen assessed as inhibition of noradrenaline-induced contractions after 0.5 hrs in presence of alpha2/beta adrenoceptor blocker yohimbine, propranolol by Schild plot analysis
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Spleen
Activity Charts
Bioactivity
Activity Types for Assay ALA4431083
Kd
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 461.56 | 3.90 | 3.90 |
| 431.54 | 3.89 | 3.89 |