Basic Information
ID: ALA4432093
Type: ADME
Description: Intrinsic clearance in mouse liver microsomes at 1 uM preincubated for 10 mins followed by NADPH addition measured up to 30 mins by LC-MS/MS analysis
Format: BAO_0000251
Organism: Mus musculus
Tissue: Liver
Subcellular Fraction: Microsome
Target: ADMET(ALA612558)
Document: ALA4431325
Intrinsic clearance in mouse liver microsomes at 1 uM preincubated for 10 mins followed by NADPH addition measured up to 30 mins by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4432093
CL
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 458.56 | 3.09 | 3.09 |
| 508.52 | 2.86 | 2.86 |
| 415.49 | 1.62 | 1.62 |
| 428.53 | 3.46 | 3.46 |
| 397.48 | 2.66 | 2.66 |
| 464.51 | 3.71 | 3.71 |
| 448.50 | 2.45 | 2.45 |
| 487.43 | 3.01 | 3.01 |
| 444.53 | 2.43 | 2.43 |
| 352.42 | 2.73 | 2.73 |
| 405.50 | 2.26 | 2.26 |
| 474.51 | 1.76 | 1.76 |
| 361.85 | 3.51 | 3.51 |
| 432.48 | 1.99 | 1.99 |
| 429.52 | 1.88 | 1.88 |
| 464.54 | 2.01 | 2.01 |
| 443.42 | 3.55 | 3.55 |
| 430.50 | 2.31 | 2.31 |
| 430.51 | 2.31 | 2.31 |
| 458.51 | 2.52 | 2.52 |
| 363.39 | 3.13 | 3.13 |
| 439.52 | 3.28 | 3.28 |
| 458.56 | 3.09 | 3.09 |
| 478.57 | 1.70 | 1.70 |
| 416.48 | 2.22 | 2.22 |
| 429.52 | 1.88 | 1.88 |
| 494.50 | 2.77 | 2.77 |
| 443.50 | 1.41 | 1.41 |
| 450.49 | 3.32 | 3.32 |
| 430.51 | 2.04 | 2.04 |
| 458.51 | 2.52 | 2.52 |
| 458.51 | 2.52 | 2.52 |
| 411.46 | 2.87 | 2.87 |
| 464.51 | 3.71 | 3.71 |
| 444.49 | 1.83 | 1.83 |
| 482.50 | 3.86 | 3.86 |
| 474.51 | 1.76 | 1.76 |
| 431.49 | 2.78 | 2.78 |
| 442.52 | 2.45 | 2.45 |