Intrinsic clearance in human liver microsomes at 1 uM preincubated for 10 mins followed by NADPH addition measured up to 30 mins by LC-MS/MS analysis

Basic Information

ID: ALA4432100

Type: ADME

Description: Intrinsic clearance in human liver microsomes at 1 uM preincubated for 10 mins followed by NADPH addition measured up to 30 mins by LC-MS/MS analysis

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsome

Target: ADMET(ALA612558)

Document: ALA4431325

Intrinsic clearance in human liver microsomes at 1 uM preincubated for 10 mins followed by NADPH addition measured up to 30 mins by LC-MS/MS analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4432100

Total(6)

Parent Molecular Weight	ALogP	Polar Surface Area
508.52	2.86	2.86
474.51	1.76	1.76
458.51	2.52	2.52
494.50	2.77	2.77
458.51	2.52	2.52
474.51	1.76	1.76

Parent Molecular Weight

ALogP

Polar Surface Area

508.52

2.86

474.51

1.76

458.51

2.52

494.50

2.77