Basic Information
ID: ALA4432149
Type: Binding
Description: Inhibition of GARFTase/AICARFTase in human KB cells expressing RFC/FR-alpha/PCFT assessed as cell growth inhibition measured after 96 hrs in presence of 10 uM thymidine by Cell-Titer Blue fluorescence analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4432149
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 442.43 | 0.54 | 0.54 |
| 484.47 | 0.48 | 0.48 |
| 443.42 | 0.50 | 0.50 |
| 459.48 | 1.22 | 1.22 |
| 470.44 | 0.09 | 0.09 |
| 538.44 | 1.02 | 1.02 |