Basic Information
ID: ALA4432181
Type: Binding
Description: Inhibition of MB-COMT in Wistar rat brain assessed as metanephrine formation preincubated for 20 mins followed by addition of adrenaline as substrate and SAM measured after 15 mins by chromatographic analysis
Organism: Rattus norvegicus
Strain: Wistar
Tissue: Brain
Activity Charts
Bioactivity
Activity Types for Assay ALA4432181
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 180.16 | 1.20 | 1.20 |
| 305.29 | 1.78 | 1.78 |
| 284.31 | 2.90 | 2.90 |
| 270.28 | 2.85 | 2.85 |
| 225.16 | 1.10 | 1.10 |
| 273.24 | 2.55 | 2.55 |
| 329.31 | 2.81 | 2.81 |
| 253.21 | 1.58 | 1.58 |
| 353.33 | 2.27 | 2.27 |
| 340.29 | 2.66 | 2.66 |
| 315.28 | 2.76 | 2.76 |
| 339.31 | 2.23 | 2.23 |
| 325.27 | 1.52 | 1.52 |
| 269.17 | 0.56 | 0.56 |
| 250.17 | 1.00 | 1.00 |
| 354.32 | 2.70 | 2.70 |