Basic Information
ID: ALA4432252
Type: Binding
Description: Inhibition of full length human KDM5A using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 1 uM of 2-OG as co-substrate by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4432252
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 233.22 | 1.82 | 1.82 |
| 186.17 | 1.11 | 1.11 |
| 218.26 | 1.68 | 1.68 |
| 233.23 | 0.38 | 0.38 |
| 234.21 | 0.81 | 0.81 |
| 215.13 | 1.34 | 1.34 |
| 233.23 | 0.33 | 0.33 |
| 190.20 | 1.19 | 1.19 |
| 219.20 | -0.01 | -0.01 |
| 247.25 | 0.77 | 0.77 |
| 259.26 | 0.86 | 0.86 |
| 162.15 | 0.63 | 0.63 |
| 187.16 | 0.50 | 0.50 |
| 295.30 | 1.56 | 1.56 |
| 247.25 | 0.72 | 0.72 |