Basic Information
ID: ALA4432448
Type: Functional
Description: Cytotoxicity against human NCI-H1975 cells harboring EGFR L858R/T790M double mutant assessed as growth inhibition after 72 hrs by MTT assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: NCI-H1975
Target: NCI-H1975(ALA614348)
Document: ALA4431348
Cytotoxicity against human NCI-H1975 cells harboring EGFR L858R/T790M double mutant assessed as growth inhibition after 72 hrs by MTT assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4432448
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 393.44 | 3.41 | 3.41 |
| 446.91 | 4.28 | 4.28 |
| 483.93 | 3.78 | 3.78 |
| 441.89 | 4.01 | 4.01 |
| 481.96 | 4.93 | 4.93 |
| 481.96 | 4.93 | 4.93 |
| 478.92 | 4.73 | 4.73 |
| 510.01 | 5.57 | 5.57 |
| 495.99 | 5.32 | 5.32 |
| 464.89 | 4.34 | 4.34 |
| 495.99 | 5.18 | 5.18 |
| 469.95 | 4.79 | 4.79 |
| 511.00 | 4.09 | 4.09 |
| 495.99 | 5.32 | 5.32 |
| 483.98 | 5.18 | 5.18 |
| 455.92 | 4.40 | 4.40 |
| 496.97 | 3.69 | 3.69 |
| 467.93 | 4.54 | 4.54 |
| 497.96 | 4.17 | 4.17 |
| 510.01 | 5.71 | 5.71 |