Basic Information
ID: ALA4432468
Type: Binding
Description: Inhibition of SERT in rat striatal synaptosomes assessed as reduction in [3H]5-HT uptake preincubated for 5 mins followed by [3H]5-HT addition measured after 10 mins by liquid scintillation spectrometric analysis
Format: BAO_0000220
Organism: Rattus norvegicus
Tissue: Striatum
Subcellular Fraction: Synaptosomes
Target: Serotonin transporter(ALA313)
Document: ALA4431349
Inhibition of SERT in rat striatal synaptosomes assessed as reduction in [3H]5-HT uptake preincubated for 5 mins followed by [3H]5-HT addition measured after 10 mins by liquid scintillation spectrometric analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4432468
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 321.46 | 4.75 | 4.75 |
| 436.25 | 4.40 | 4.40 |
| 427.42 | 3.11 | 3.11 |
| 397.39 | 3.10 | 3.10 |