Basic Information
ID: ALA4432509
Type: Binding
Description: Inhibition of 6x-His tagged human recombinant full length Hsp90alpha ATPase preincubated for 0.5 hrs followed by ATP addition measured after 30 mins by HTRF assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Heat shock protein HSP 90-alpha(ALA3880)
Document: ALA4431352
Inhibition of 6x-His tagged human recombinant full length Hsp90alpha ATPase preincubated for 0.5 hrs followed by ATP addition measured after 30 mins by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4432509
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 616.76 | 1.91 | 1.91 |
| 628.76 | 7.24 | 7.24 |
| 380.44 | 3.76 | 3.76 |
| 364.44 | 4.05 | 4.05 |
| 336.39 | 3.27 | 3.27 |
| 324.33 | 2.20 | 2.20 |
| 394.42 | 3.20 | 3.20 |
| 438.48 | 3.51 | 3.51 |
| 366.41 | 3.28 | 3.28 |
| 414.89 | 3.97 | 3.97 |
| 396.44 | 3.46 | 3.46 |
| 412.39 | 1.64 | 1.64 |
| 430.48 | 2.61 | 2.61 |
| 396.44 | 2.73 | 2.73 |
| 394.47 | 4.06 | 4.06 |
| 308.33 | 2.49 | 2.49 |
| 466.53 | 3.99 | 3.99 |
| 386.83 | 3.20 | 3.20 |
| 352.39 | 2.98 | 2.98 |
| 408.45 | 3.32 | 3.32 |
| 422.48 | 3.97 | 3.97 |
| 396.40 | 1.76 | 1.76 |
| 458.53 | 3.39 | 3.39 |
| 368.39 | 1.95 | 1.95 |