Basic Information
ID: ALA4432632
Type: Binding
Description: Inhibition of C-terminal biotin-tagged streptavidin labelled human MDM2 ( 2 to 188 residues)/Cy5-labelled p53 (18 to 26 residues)(unknown origin) interaction after 15 mins by TR-FRET assay
Format: BAO_0000224
Organism: Homo sapiens
Target: Tumour suppressor p53/oncoprotein Mdm2(ALA1907611)
Document: ALA4431357
Inhibition of C-terminal biotin-tagged streptavidin labelled human MDM2 ( 2 to 188 residues)/Cy5-labelled p53 (18 to 26 residues)(unknown origin) interaction after 15 mins by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4432632
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 581.50 | 5.89 | 5.89 |
| 337.81 | 4.43 | 4.43 |
| 593.55 | 7.31 | 7.31 |
| 520.46 | 7.68 | 7.68 |
| 520.46 | 7.68 | 7.68 |
| 414.34 | 6.21 | 6.21 |
| 386.28 | 5.59 | 5.59 |
| 400.31 | 5.76 | 5.76 |
| 358.23 | 4.77 | 4.77 |