Basic Information
ID: ALA4432658
Type: Functional
Description: Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment preincubated for 30 mins followed by addition of CP55940 for 90 mins by chemiluminescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO-K1
Target: Cannabinoid CB1 receptor(ALA218)
Document: ALA4431361
Negative allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940 induced beta arrestin recruitment preincubated for 30 mins followed by addition of CP55940 for 90 mins by chemiluminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4432658
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 409.96 | 5.35 | 5.35 |
| 405.52 | 4.38 | 4.38 |
| 337.45 | 1.48 | 1.48 |
| 405.95 | 3.97 | 3.97 |
| 433.87 | 4.64 | 4.64 |
| 314.41 | 3.26 | 3.26 |
| 447.99 | 3.74 | 3.74 |
| 440.55 | 3.72 | 3.72 |
| 323.42 | 1.09 | 1.09 |
| 316.38 | 2.66 | 2.66 |
| 380.44 | 4.45 | 4.45 |
| 406.46 | 4.01 | 4.01 |
| 380.44 | 4.45 | 4.45 |
| 433.87 | 4.64 | 4.64 |
| 334.83 | 3.61 | 3.61 |
| 346.41 | 2.66 | 2.66 |
| 407.50 | 4.11 | 4.11 |
| 432.88 | 5.25 | 5.25 |
| 397.54 | 3.99 | 3.99 |
| 460.33 | 4.61 | 4.61 |
| 405.48 | 3.41 | 3.41 |
| 334.83 | 3.61 | 3.61 |
| 494.47 | 5.36 | 5.36 |
| 411.46 | 3.86 | 3.86 |
| 392.48 | 3.81 | 3.81 |
| 432.88 | 5.25 | 5.25 |
| 330.41 | 2.96 | 2.96 |
| 364.85 | 3.62 | 3.62 |
| 368.38 | 3.97 | 3.97 |
| 314.41 | 3.00 | 3.00 |
| 306.43 | 3.33 | 3.33 |
| 422.51 | 3.81 | 3.81 |
| 399.52 | 2.83 | 2.83 |
| 301.37 | 2.35 | 2.35 |
| 428.92 | 5.41 | 5.41 |
| 362.45 | 4.31 | 4.31 |
| 441.35 | 5.08 | 5.08 |
| 406.51 | 4.46 | 4.46 |
| 417.49 | 4.19 | 4.19 |
| 394.47 | 5.01 | 5.01 |
| 363.44 | 3.71 | 3.71 |
| 380.44 | 4.45 | 4.45 |
| 459.34 | 5.22 | 5.22 |
| 474.99 | 4.37 | 4.37 |
| 412.90 | 3.94 | 3.94 |
| 300.38 | 2.95 | 2.95 |
| 301.37 | 2.35 | 2.35 |
| 357.48 | 3.06 | 3.06 |
| 446.02 | 4.90 | 4.90 |
| 478.32 | 4.75 | 4.75 |
| 383.30 | 4.52 | 4.52 |
| 428.92 | 5.41 | 5.41 |
| 376.48 | 4.62 | 4.62 |
| 415.88 | 4.50 | 4.50 |
| 396.90 | 4.97 | 4.97 |
| 368.48 | 4.37 | 4.37 |
| 408.48 | 4.03 | 4.03 |
| 392.48 | 4.32 | 4.32 |
| 369.27 | 4.26 | 4.26 |
| 376.48 | 4.62 | 4.62 |
| 422.51 | 4.33 | 4.33 |