Basic Information
ID: ALA4432798
Type: Binding
Description: Inhibition of PARP-1 in human A549 cells assessed as potentiation of temozolomide induced growth inhibition by measuring ratio of temozolomide EC50 at 0.5 uM after 72 hrs by SRB assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: A549
Target: Poly [ADP-ribose] polymerase-1(ALA3105)
Document: ALA4431370
Inhibition of PARP-1 in human A549 cells assessed as potentiation of temozolomide induced growth inhibition by measuring ratio of temozolomide EC50 at 0.5 uM after 72 hrs by SRB assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4432798
PF50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 244.30 | 1.26 | 1.26 |
| 327.43 | 2.01 | 2.01 |
| 307.36 | 1.56 | 1.56 |
| 321.38 | 1.95 | 1.95 |
| 348.41 | 1.25 | 1.25 |