Basic Information
ID: ALA4433045
Type: Binding
Description: Inhibition of SYK in human B cells assessed as suppression of anti-IgM-induced CD69 surface expression preincubated for 30 mins followed by anti-IgM addition measured after 3.5 hrs by flow cytometric analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4433045
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 364.45 | 2.53 | 2.53 |
| 341.42 | 0.37 | 0.37 |
| 307.40 | 3.15 | 3.15 |
| 337.43 | 2.30 | 2.30 |
| 359.38 | 2.08 | 2.08 |
| 338.42 | 2.34 | 2.34 |
| 348.33 | 3.13 | 3.13 |
| 309.38 | 1.83 | 1.83 |
| 365.44 | 1.55 | 1.55 |
| 349.44 | 2.71 | 2.71 |
| 323.40 | 3.00 | 3.00 |
| 327.44 | 0.85 | 0.85 |
| 339.40 | 0.71 | 0.71 |
| 338.42 | 0.74 | 0.74 |
| 332.45 | 4.02 | 4.02 |
| 323.40 | 1.84 | 1.84 |
| 333.44 | 3.41 | 3.41 |
| 399.45 | 2.81 | 2.81 |
| 325.38 | 0.83 | 0.83 |
| 362.48 | 3.17 | 3.17 |
| 378.48 | 1.47 | 1.47 |
| 378.48 | 1.47 | 1.47 |
| 337.39 | 1.44 | 1.44 |
| 361.49 | 3.77 | 3.77 |
| 360.37 | 2.05 | 2.05 |
| 359.38 | 2.08 | 2.08 |
| 363.47 | 2.72 | 2.72 |
| 363.47 | 2.56 | 2.56 |
| 399.45 | 2.81 | 2.81 |
| 362.48 | 3.09 | 3.09 |
| 360.37 | 2.05 | 2.05 |
| 309.38 | 1.83 | 1.83 |
| 365.44 | 1.55 | 1.55 |
| 333.44 | 3.41 | 3.41 |
| 399.45 | 2.81 | 2.81 |
| 364.45 | 2.53 | 2.53 |
| 339.47 | 3.47 | 3.47 |
| 324.39 | 1.80 | 1.80 |