Assay Report Card

Basic Information

ID: ALA4433086

Type: Binding

Description: Binding affinity to XIAP BIR3 domain in Smac mimetic-sensitive human MDA-MB-231 cells assessed as increase in cleaved caspase-3 expression at 5 uM after 24 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: MDA-MB-231

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
392.502.392.39
609.773.573.57
801.993.133.13
758.923.553.55
758.923.553.55
801.993.133.13
625.772.692.69
749.913.503.50