Assay Report Card

Basic Information

ID: ALA4433094

Type: Binding

Description: Binding affinity to XIAP BIR3 domain in Smac mimetic-resistant human MDA-MB-453 cells assessed as increase in cleaved PARP expression at 5 uM after 24 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: MDA-MB-453

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
609.773.573.57
801.993.133.13
758.923.553.55
749.913.503.50