Basic Information
ID: ALA4433126
Type: Binding
Description: Inhibition of Keap1-Nrf2 interaction in human HepG2-ARE-C8 cells assessed as activation of Nrf2-ARE activity at 5 uM after 12 hrs by luciferase reporter gene assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Target: Keap1/Nrf2(ALA3038498)
Document: ALA4431393
Inhibition of Keap1-Nrf2 interaction in human HepG2-ARE-C8 cells assessed as activation of Nrf2-ARE activity at 5 uM after 12 hrs by luciferase reporter gene assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4433126
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 668.71 | 3.32 | 3.32 |
| 698.74 | 2.16 | 2.16 |
| 630.71 | 4.19 | 4.19 |
| 714.79 | 3.78 | 3.78 |
| 640.74 | 3.13 | 3.13 |
| 716.77 | 2.57 | 2.57 |
| 696.76 | 3.49 | 3.49 |
| 628.73 | 4.41 | 4.41 |
| 666.74 | 2.12 | 2.12 |