Reversible binding affinity to D5D in Sprague-Dawley rat liver microsomes assessed as compound bound to protein at 6 nM preincubated for 150 mins foll...

Basic Information

ID: ALA4433179

Type: Binding

Description: Reversible binding affinity to D5D in Sprague-Dawley rat liver microsomes assessed as compound bound to protein at 6 nM preincubated for 150 mins followed by 2 fold dilution by 10 uM of T-3364366 measured after 21 hrs by liquid scintillation counting relative to control

Format: BAO_0000251

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Tissue: Liver

Subcellular Fraction: Microsomes

Target:  Fatty acid desaturase 1(ALA5727)

Document:  ALA4431397

Reversible binding affinity to D5D in Sprague-Dawley rat liver microsomes assessed as compound bound to protein at 6 nM preincubated for 150 mins followed by 2 fold dilution by 10 uM of T-3364366 measured after 21 hrs by liquid scintillation counting relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
443.473.623.62