Basic Information
ID: ALA4433180
Type: Binding
Description: Reversible binding affinity to D5D in Sprague-Dawley rat liver microsomes assessed as dissociation half life at 6 nM preincubated for 150 mins followed by 2 fold dilution by 10 uM of T-3364366 by liquid scintillation counting
Format: BAO_0000251
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Fatty acid desaturase 1(ALA5727)
Document: ALA4431397
Reversible binding affinity to D5D in Sprague-Dawley rat liver microsomes assessed as dissociation half life at 6 nM preincubated for 150 mins followed by 2 fold dilution by 10 uM of T-3364366 by liquid scintillation counting: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4433180
T1/2
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 443.47 | 3.62 | 3.62 |