Basic Information
ID: ALA4433522
Type: Binding
Description: Inhibition of human SIRT3 assessed as reduction in deacetylase activity using acetylated H3K9 as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins by UV-HPLC analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4433522
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 122.13 | 0.18 | 0.18 |
| 581.87 | 8.71 | 8.71 |
| 500.67 | 4.45 | 4.45 |
| 554.80 | 6.70 | 6.70 |
| 526.75 | 5.92 | 5.92 |
| 598.85 | 7.18 | 7.18 |
| 582.86 | 7.48 | 7.48 |
| 542.75 | 5.62 | 5.62 |
| 472.61 | 3.67 | 3.67 |
| 498.69 | 5.13 | 5.13 |
| 512.72 | 5.52 | 5.52 |
| 444.56 | 2.89 | 2.89 |
| 570.80 | 6.40 | 6.40 |