Basic Information
ID: ALA4433546
Type: Functional
Description: Antitumor activity against human HCT116 cells harboring KRAS G13D mutant xenografted in NSG mouse assessed as tumor growth inhibition by measuring reduction in tumor volume at 100 mg/kg, ip administered daily for 12 days and measured post-last dose relative to control
Organism: Homo sapiens
Cell type: HCT-116
Activity Charts
Bioactivity
Activity Types for Assay ALA4433546
TGI
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 554.80 | 6.70 | 6.70 |
| 526.75 | 5.92 | 5.92 |