Assay Report Card

Basic Information

ID: ALA4433548

Type: Toxicity

Description: Toxicity in NSG mouse xenografted with human HCT116 cells harboring KRAS G13D mutant assessed as body weight loss at 25 mg/kg, ip administered daily for 12 days measured during compound dosing

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
554.806.706.70
526.755.925.92