Basic Information
ID: ALA4433552
Type: Binding
Description: Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HepG2
Target: Bile acid receptor FXR(ALA2047)
Document: ALA4433207
Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4433552
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 542.85 | 8.87 | 8.87 |
| 392.58 | 4.48 | 4.48 |
| 420.63 | 5.11 | 5.11 |
| 392.28 | 5.84 | 5.84 |
| 482.36 | 7.72 | 7.72 |
| 387.27 | 6.22 | 6.22 |
| 392.28 | 5.84 | 5.84 |
| 362.26 | 6.35 | 6.35 |
| 498.41 | 7.42 | 7.42 |
| 526.42 | 7.72 | 7.72 |
| 440.35 | 5.75 | 5.75 |
| 493.39 | 7.80 | 7.80 |
| 406.27 | 6.05 | 6.05 |
| 387.27 | 6.22 | 6.22 |
| 526.42 | 7.72 | 7.72 |
| 420.29 | 6.14 | 6.14 |
| 498.41 | 7.42 | 7.42 |
| 496.39 | 7.80 | 7.80 |
| 493.39 | 7.80 | 7.80 |
| 468.38 | 7.51 | 7.51 |
| 512.39 | 7.63 | 7.63 |
| 420.29 | 6.14 | 6.14 |
| 512.39 | 7.63 | 7.63 |
| 406.27 | 6.05 | 6.05 |