Basic Information
ID: ALA4433724
Type: Binding
Description: Antagonist activity at human FXR transfected in HepG2 cells assessed as inhibition of CDCA-induced receptor transactivation by luciferase reporter assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HepG2
Target: Bile acid receptor FXR(ALA2047)
Document: ALA4433214
Antagonist activity at human FXR transfected in HepG2 cells assessed as inhibition of CDCA-induced receptor transactivation by luciferase reporter assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4433724
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 351.45 | 3.84 | 3.84 |
| 265.32 | 3.31 | 3.31 |
| 337.42 | 3.80 | 3.80 |
| 337.38 | 3.50 | 3.50 |
| 279.34 | 3.36 | 3.36 |
| 351.45 | 4.19 | 4.19 |
| 279.34 | 3.70 | 3.70 |
| 337.42 | 3.80 | 3.80 |
| 365.48 | 4.58 | 4.58 |
| 323.40 | 3.41 | 3.41 |
| 337.42 | 3.45 | 3.45 |
| 365.43 | 3.93 | 3.93 |
| 351.45 | 4.19 | 4.19 |