Assay Report Card

Basic Information

ID: ALA4433839

Type: Binding

Description: Inhibition of human HCN4 expressed in HEK293 cells assessed as reduction in hyperpolarization activated current at 5 uM at holding potential of -80 mV by patch clamp assay relative to control

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
492.624.344.34
510.684.524.52
508.664.604.60
496.654.134.13
496.654.134.13
482.624.094.09
512.653.973.97
618.775.685.68