Basic Information
ID: ALA4433979
Type: Functional
Description: Positive allosteric modulator activity at human T1R2/T1R3 expressed in PEAKrapid cells assessed as potentiation of sucrose-induced intracellular calcium influx by measuring sucrose EC50 at 30 uM measured for 120 secs by fluorescence based assay relative to FEMA4774
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4433979
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 419.53 | 2.27 | 2.27 |
| 467.57 | 2.72 | 2.72 |
| 333.34 | 2.65 | 2.65 |
| 391.47 | 1.49 | 1.49 |
| 377.45 | 1.10 | 1.10 |
| 332.36 | 1.22 | 1.22 |
| 332.36 | 2.08 | 2.08 |
| 346.39 | 1.61 | 1.61 |
| 303.32 | 1.89 | 1.89 |
| 433.55 | 2.52 | 2.52 |
| 317.35 | 2.28 | 2.28 |
| 419.53 | 2.13 | 2.13 |
| 377.45 | 1.10 | 1.10 |
| 275.26 | 1.26 | 1.26 |
| 372.43 | 2.15 | 2.15 |
| 405.50 | 1.74 | 1.74 |
| 391.47 | 1.49 | 1.49 |
| 419.53 | 2.13 | 2.13 |
| 360.37 | 1.01 | 1.01 |
| 346.39 | 1.61 | 1.61 |