Basic Information
ID: ALA4434088
Type: Binding
Description: Inhibition of human full length TNIK(1-1360)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubated for 30 mins followed by substrate addition and measured after 120 mins by ADP-Glo Reagent based method
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf21
Target: TRAF2- and NCK-interacting kinase(ALA4527)
Document: ALA4433232
Inhibition of human full length TNIK(1-1360)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubated for 30 mins followed by substrate addition and measured after 120 mins by ADP-Glo Reagent based method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4434088
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 340.40 | 3.11 | 3.11 |
| 368.46 | 3.59 | 3.59 |
| 384.48 | 4.49 | 4.49 |
| 319.14 | 3.18 | 3.18 |
| 356.43 | 4.01 | 4.01 |
| 225.23 | 2.83 | 2.83 |