Basic Information
ID: ALA4434177
Type: Functional
Description: Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by cell titer glo-based luminescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HCT-116
Target: HCT-116(ALA394)
Document: ALA4433236
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by cell titer glo-based luminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4434177
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 382.25 | 2.45 | 2.45 |
| 797.04 | 4.26 | 4.26 |
| 804.68 | 4.73 | 4.73 |
| 615.40 | 4.28 | 4.28 |
| 776.62 | 3.62 | 3.62 |
| 719.53 | 3.98 | 3.98 |
| 705.50 | 3.68 | 3.68 |
| 655.46 | 4.49 | 4.49 |
| 572.33 | 4.02 | 4.02 |
| 669.44 | 4.13 | 4.13 |
| 669.44 | 4.13 | 4.13 |
| 641.43 | 4.49 | 4.49 |
| 684.62 | 2.52 | 2.52 |
| 655.46 | 4.49 | 4.49 |
| 615.40 | 4.28 | 4.28 |
| 677.42 | 5.60 | 5.60 |
| 726.54 | 4.06 | 4.06 |
| 636.61 | 2.37 | 2.37 |
| 655.46 | 4.88 | 4.88 |
| 641.43 | 4.49 | 4.49 |
| 762.59 | 3.61 | 3.61 |
| 772.20 | 3.35 | 3.35 |
| 707.51 | 3.90 | 3.90 |
| 641.43 | 4.49 | 4.49 |
| 669.44 | 4.13 | 4.13 |
| 705.50 | 3.68 | 3.68 |
| 726.54 | 4.06 | 4.06 |
| 779.65 | 4.34 | 4.34 |
| 712.56 | 4.42 | 4.42 |
| 655.46 | 4.49 | 4.49 |
| 719.53 | 3.69 | 3.69 |
| 655.46 | 4.88 | 4.88 |
| 776.62 | 3.95 | 3.95 |
| 677.42 | 5.60 | 5.60 |
| 762.59 | 3.61 | 3.61 |
| 705.50 | 3.68 | 3.68 |
| 783.78 | 2.33 | 2.33 |
| 753.76 | 2.32 | 2.32 |
| 734.52 | 5.53 | 5.53 |
| 657.48 | 4.71 | 4.71 |
| 698.53 | 4.42 | 4.42 |
| 747.68 | 2.72 | 2.72 |
| 607.42 | 2.81 | 2.81 |
| 655.46 | 4.49 | 4.49 |
| 762.59 | 3.61 | 3.61 |
| 734.52 | 5.53 | 5.53 |
| 739.94 | 4.33 | 4.33 |
| 550.32 | 2.88 | 2.88 |
| 748.55 | 5.84 | 5.84 |
| 762.59 | 3.61 | 3.61 |
| 719.53 | 4.02 | 4.02 |
| 776.62 | 3.92 | 3.92 |
| 719.53 | 3.69 | 3.69 |
| 655.46 | 4.49 | 4.49 |
| 705.50 | 3.68 | 3.68 |
| 762.59 | 3.61 | 3.61 |
| 641.43 | 4.49 | 4.49 |
| 729.68 | 2.58 | 2.58 |
| 698.53 | 4.42 | 4.42 |
| 693.71 | 2.30 | 2.30 |
| 607.42 | 2.81 | 2.81 |
| 712.56 | 4.42 | 4.42 |
| 701.08 | 3.03 | 3.03 |
| 691.45 | 5.91 | 5.91 |
| 705.50 | 3.68 | 3.68 |
| 629.42 | 3.96 | 3.96 |
| 758.18 | 2.96 | 2.96 |
| 735.73 | 2.81 | 2.81 |
| 572.33 | 4.02 | 4.02 |
| 726.69 | 2.40 | 2.40 |
| 677.42 | 5.60 | 5.60 |
| 776.62 | 3.62 | 3.62 |
| 698.53 | 4.42 | 4.42 |
| 558.30 | 4.35 | 4.35 |
| 669.44 | 4.13 | 4.13 |
| 734.52 | 5.53 | 5.53 |
| 550.32 | 2.88 | 2.88 |
| 726.54 | 4.06 | 4.06 |
| 705.50 | 3.68 | 3.68 |
| 741.72 | 2.45 | 2.45 |
| 655.46 | 4.49 | 4.49 |
| 838.69 | 5.28 | 5.28 |
| 698.53 | 4.42 | 4.42 |
| 735.53 | 3.69 | 3.69 |
| 737.76 | 2.24 | 2.24 |
| 607.42 | 2.81 | 2.81 |
| 677.42 | 5.60 | 5.60 |
| 690.58 | 2.79 | 2.79 |
| 629.42 | 3.96 | 3.96 |
| 672.59 | 2.65 | 2.65 |
| 712.56 | 4.81 | 4.81 |
| 792.62 | 3.62 | 3.62 |
| 734.52 | 5.53 | 5.53 |
| 762.59 | 3.61 | 3.61 |
| 726.54 | 4.06 | 4.06 |
| 705.50 | 3.68 | 3.68 |
| 558.30 | 4.35 | 4.35 |
| 550.32 | 2.88 | 2.88 |
| 712.56 | 4.81 | 4.81 |
| 722.55 | 4.41 | 4.41 |