Assay Report Card

Basic Information

ID: ALA4434190

Type: Binding

Description: Inhibition of recombinant human topoisomerase-2beta expressed in Saccharomyces cerevisiae assessed as increase in double-stranded DNA cleavage at 0 to 1000 uM using supercoiled pBR322 DNA as substrate incubated for 6 mins measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis method relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
526.745.945.94