Assay Report Card

Basic Information

ID: ALA4434193

Type: Binding

Description: Poison activity at recombinant human topoisomerase-2alpha expressed in Saccharomyces cerevisiae assessed as stabilization of DNA-enzyme cleavage complex at 500 uM using supercoiled pBR322 DNA as substrate incubated for 10 mins and measured after 0 to 240 mins by ethidium bromide staining based agarose gel electrophoresis method

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
526.745.945.94