Basic Information
ID: ALA4434195
Type: Binding
Description: Covalent poison activity at recombinant human topoisomerase-2alpha expressed in Saccharomyces cerevisiae assessed as decrease in pBR322 DNA cleavage up to 1000 uM using supercoiled pBR322 DNA as substrate incubated for 6 mins and measured after 30 mins in presence of dithiothreitol by ethidium bromide staining based agarose gel electrophoresis method relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4434195
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 526.74 | 5.94 | 5.94 |