Basic Information
ID: ALA4434202
Type: Binding
Description: Covalent poison activity at recombinant human N-terminal topoisomerase-2alpha C-terminal domain deletion mutant expressed in Saccharomyces cerevisiae assessed as increase in pBR322 DNA cleavage at 0 to 1000 uM using supercoiled pBR322 DNA as substrate incubated for 6 mins and measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis method relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4434202
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 526.74 | 5.94 | 5.94 |