Basic Information
ID: ALA4434203
Type: Binding
Description: Poison activity at recombinant human topoisomerase-2alpha expressed in Saccharomyces cerevisiae assessed as enzyme inactivation time by measuring increase in double-stranded DNA cleavage at 500 uM using supercoiled pBR322 DNA as substrate preincubated for 120 sec followed by substrate addition incubated for 6 mins and measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis method relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4434203
T1/2
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 526.74 | 5.94 | 5.94 |