Basic Information
ID: ALA4434259
Type: Binding
Description: Inhibition of GST-tagged truncated human LRRK2 G2019S mutant pre-incubated for 15 mins before fluorescein-labeled peptide substrate LRRKtide addition and measured after 90 mins by LRRK2 Km ATP LanthaScreen assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Leucine-rich repeat serine/threonine-protein kinase 2(ALA1075104)
Document: ALA4433243
Inhibition of GST-tagged truncated human LRRK2 G2019S mutant pre-incubated for 15 mins before fluorescein-labeled peptide substrate LRRKtide addition and measured after 90 mins by LRRK2 Km ATP LanthaScreen assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4434259
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.55 | 2.38 | 2.38 |
| 455.57 | 3.06 | 3.06 |
| 428.54 | 3.75 | 3.75 |
| 426.52 | 3.50 | 3.50 |
| 414.51 | 3.36 | 3.36 |
| 418.48 | 3.06 | 3.06 |