Basic Information
ID: ALA4434260
Type: Binding
Description: Inhibition of His-tagged human MTHFD2 ( 36 to 350 residues) expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before folitixorin and NAD+ addition measured after 15 mins by NAD(P)H-Glo detection reagent based luminescence assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(ALA3621036)
Document: ALA4433244
Inhibition of His-tagged human MTHFD2 ( 36 to 350 residues) expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before folitixorin and NAD+ addition measured after 15 mins by NAD(P)H-Glo detection reagent based luminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4434260
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 471.43 | 0.05 | 0.05 |