Basic Information
ID: ALA4434261
Type: Binding
Description: Inhibition of His-tagged human MTHFD1 ( 1 to 306 residues) expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before folitixorin and NADP+ addition measured after 15 mins by NAD(P)H-Glo detection reagent based luminescence assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Methylenetetrahydrofolate dehydrogenase(ALA2541)
Document: ALA4433244
Inhibition of His-tagged human MTHFD1 ( 1 to 306 residues) expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before folitixorin and NADP+ addition measured after 15 mins by NAD(P)H-Glo detection reagent based luminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4434261
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 471.43 | 0.05 | 0.05 |