Basic Information
ID: ALA4434271
Type: Binding
Description: Agonist activity at human Kv7.4/Kv7.5 expressed in HEK293 cells assessed as drug concentration that doubles the conductance at voltage leading to 15% channel activation at holding potential of at -80 mV by whole cell patch clamp electrophysiology assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4434271
EC2
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 303.34 | 3.59 | 3.59 |
| 304.32 | 2.98 | 2.98 |
| 371.33 | 4.61 | 4.61 |
| 389.32 | 4.75 | 4.75 |
| 371.33 | 4.61 | 4.61 |
| 437.32 | 5.17 | 5.17 |
| 384.33 | 4.14 | 4.14 |
| 383.35 | 4.75 | 4.75 |
| 419.33 | 5.03 | 5.03 |
| 420.31 | 4.42 | 4.42 |
| 372.32 | 4.00 | 4.00 |
| 419.33 | 5.03 | 5.03 |
| 439.33 | 5.63 | 5.63 |
| 401.34 | 4.89 | 4.89 |
| 384.33 | 4.14 | 4.14 |
| 372.32 | 4.00 | 4.00 |
| 397.33 | 3.87 | 3.87 |
| 429.39 | 6.25 | 6.25 |
| 420.31 | 4.42 | 4.42 |
| 371.33 | 4.61 | 4.61 |
| 402.32 | 4.28 | 4.28 |
| 385.36 | 5.00 | 5.00 |