Basic Information
ID: ALA4434280
Type: Binding
Description: Binding affinity to capsid protein in Hepatitis B virus infected in human HepG2.2.15 cells assessed as inhibition of HBV DNA replication incubated for 3 days followed by replacement of fresh medium containing compound and measured after 3 days by chemiluminescent assay
Organism: Hepatitis B virus
Activity Charts
Bioactivity
Activity Types for Assay ALA4434280
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 444.89 | 3.41 | 3.41 |
| 472.94 | 4.04 | 4.04 |
| 444.89 | 3.41 | 3.41 |
| 458.91 | 3.80 | 3.80 |
| 458.91 | 3.65 | 3.65 |
| 460.89 | 2.64 | 2.64 |
| 448.85 | 3.23 | 3.23 |
| 462.93 | 2.97 | 2.97 |
| 464.87 | 4.68 | 4.68 |
| 446.86 | 2.25 | 2.25 |
| 460.89 | 2.91 | 2.91 |
| 459.90 | 2.17 | 2.17 |
| 432.40 | 2.64 | 2.64 |
| 458.91 | 3.80 | 3.80 |
| 446.86 | 2.25 | 2.25 |
| 458.91 | 3.80 | 3.80 |
| 458.91 | 3.80 | 3.80 |
| 446.86 | 2.25 | 2.25 |
| 457.89 | 2.72 | 2.72 |
| 460.89 | 2.38 | 2.38 |
| 458.91 | 4.14 | 4.14 |