Basic Information
ID: ALA4434603
Type: ADME
Description: Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin pre-incubated for 10 mins before NADPH addition and measured after 10 mins by LC/MS/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 2C19(ALA3622)
Document: ALA4433269
Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin pre-incubated for 10 mins before NADPH addition and measured after 10 mins by LC/MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4434603
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 395.43 | 3.44 | 3.44 |
| 395.43 | 3.44 | 3.44 |