Basic Information
ID: ALA4434605
Type: ADME
Description: Inhibition of CYP3A4 in human liver microsomes using midazolam pre-incubated for 10 mins before NADPH addition and measured after 10 mins by LC/MS/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 3A4(ALA340)
Document: ALA4433269
Inhibition of CYP3A4 in human liver microsomes using midazolam pre-incubated for 10 mins before NADPH addition and measured after 10 mins by LC/MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4434605
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 395.43 | 3.44 | 3.44 |
| 395.43 | 3.44 | 3.44 |