Assay Report Card

Basic Information

ID: ALA4476936

Type: Binding

Description: Inhibition of C-terminal Avi-6x-His epitope tagged and N-terminal human RAGE signal sequence tagged recombinant human TLL2 (26 to 1015 amino acids) expressed in CHOE1A cells incubated for 60 mins with promyostatin peptide substrate by FRET based assay

Organism: Homo sapiens

Activity Charts

Bioactivity

Activity Types for Assay ALA4476936

IC50

Total(139)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
401.46	2.79	2.79
445.47	2.49	2.49
517.58	3.67	3.67
431.49	2.80	2.80
445.52	3.19	3.19
553.55	2.77	2.77
429.52	3.57	3.57
445.47	2.49	2.49
517.58	3.67	3.67
632.67	2.63	2.63
553.55	2.77	2.77
632.67	2.63	2.63
702.66	2.91	2.91
619.76	3.41	3.41
588.61	2.23	2.23
531.61	3.60	3.60
499.49	3.74	3.74
431.49	2.80	2.80
515.61	3.94	3.94
531.56	2.90	2.90
662.65	1.69	1.69
513.59	3.69	3.69
461.58	3.91	3.91
602.64	2.54	2.54
515.61	3.94	3.94
433.55	2.92	2.92
444.53	2.86	2.86
567.59	4.15	4.15
546.58	2.14	2.14
449.48	2.94	2.94
581.60	4.08	4.08
501.58	3.75	3.75
588.61	2.23	2.23
489.53	2.98	2.98
435.48	2.85	2.85
507.52	3.36	3.36
508.60	2.04	2.04
455.52	2.68	2.68
602.64	2.62	2.62
487.55	3.58	3.58
567.58	3.65	3.65
489.53	2.98	2.98
505.54	3.34	3.34
459.50	2.42	2.42
463.46	2.63	2.63
474.51	2.67	2.67
487.55	3.20	3.20
487.60	4.36	4.36
475.50	2.50	2.50
533.58	3.38	3.38
646.69	2.56	2.56
467.47	3.40	3.40
535.57	3.81	3.81
513.57	2.25	2.25
477.49	2.72	2.72
481.45	2.77	2.77
432.48	2.20	2.20
525.50	2.08	2.08
662.65	1.69	1.69
503.55	2.98	2.98
632.67	2.63	2.63
446.46	2.70	2.70
646.69	3.02	3.02
426.47	2.67	2.67
461.52	2.81	2.81
459.50	2.58	2.58
481.50	3.44	3.44
517.54	2.97	2.97
426.47	2.67	2.67
688.78	3.89	3.89
582.55	2.14	2.14
632.67	2.58	2.58
646.69	3.02	3.02
485.46	3.69	3.69
547.56	2.73	2.73
459.50	2.58	2.58
574.68	3.49	3.49
566.55	2.44	2.44
702.80	4.28	4.28
583.53	1.84	1.84
459.50	2.58	2.58
666.68	2.68	2.68
710.64	3.20	3.20
557.58	2.12	2.12
432.48	2.20	2.20
461.52	2.81	2.81
463.46	2.63	2.63
587.57	2.83	2.83
514.62	3.27	3.27
536.61	2.01	2.01
610.60	2.84	2.84
417.46	2.50	2.50
567.60	3.43	3.43
674.75	3.20	3.20
473.53	3.27	3.27
666.68	2.64	2.64
487.56	2.67	2.67
513.59	3.69	3.69
489.53	2.89	2.89
495.47	2.25	2.25
610.60	2.84	2.84
481.44	1.60	1.60
461.47	2.20	2.20
588.61	2.23	2.23
445.47	2.49	2.49
533.58	3.38	3.38
489.57	3.68	3.68
563.56	2.44	2.44
494.57	1.70	1.70
716.74	3.83	3.83
413.47	2.79	2.79
531.61	4.06	4.06
480.54	1.44	1.44
431.49	2.16	2.16
459.50	2.80	2.80
475.50	2.50	2.50
633.56	2.77	2.77
449.51	3.24	3.24
447.56	3.52	3.52
458.52	2.15	2.15
473.53	2.98	2.98
475.50	2.50	2.50
460.49	2.07	2.07
459.50	2.80	2.80
517.58	1.49	1.49
588.61	2.18	2.18
492.55	1.59	1.59
580.58	2.75	2.75
702.66	2.96	2.96
432.48	2.20	2.20
567.58	3.43	3.43
503.55	3.28	3.28
559.66	2.66	2.66
620.70	1.42	1.42
479.47	2.32	2.32
509.50	2.91	2.91
632.67	2.58	2.58
632.67	2.63	2.63
455.52	2.68	2.68